Anxiety in persons with the gastrointestinal illness irritable bowel syndrome is common. It is because of particular genes. IBS impacts one out of every ten individuals. It can cause stomach discomfort, bloating, and constipation, diarrhea, or both.
According to the BBC, University researchers believe that their study may prevent IBS from being incorrectly labeled as an emotional condition or all in the head. Journal of Natural Genetics published this study. It looked at almost 50,000 people who had IBS and compared their DNA to that of healthy people.
The researchers discovered at least six different genetic variations that might, at least in part, explain the gut-brain connection. We can find the majority of these in the brain. Potentially the nerves that feed the stomach, not in the gut itself. The same genetic makeup that puts people at risk for IBS also puts them at risk for mood and anxiety disorders. This includes anxiety, depression, and neuroticism, as well as sleeplessness.
Miles Parkes, a consultant gastroenterologist at Cambridge’s Addenbrookes Hospital led the gene research. IBS is still poorly understood. Even by some clinicians, and maybe wrongly classified as psychosomatic because of the overlap with worry and stress. That isn’t to say that anxiety creates IBS symptoms or that IBS causes anxiety.
Our research indicates that both diseases have genetic roots, Parkes said. Affected genes may produce physical changes in brain or nerve cells, which in turn generate symptoms in the brain and symptoms in the stomach. According to the research, the discovery might eventually contribute to the development of improved IBS testing and therapies.
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